Principles of Inheritance and Variation Question 166

166. Cri-du-chat syndrome in humans is caused by the

[2006]

(a) loss of half of the short arm of chromosome 5

(b) loss of half of the long arm of chromosome 5

(c) trisomy of $21^{s t}$ chromosome

(d) fertilization of an XX egg by a normal Y-bearing sperm

Show Answer

Answer : a

Hints & Solution

(a) Cri-du-chat syndrome in humans is caused by the partial deletion of the short arm of chromosome no. 5. This child has abnormalities in his/her facial expressions, mental retardation, they speak and cry like that of cat, heart does not work properly.



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