Principles of Inheritance and Variation Question 166
166. Cri-du-chat syndrome in humans is caused by the
[2006]
(a) loss of half of the short arm of chromosome 5
(b) loss of half of the long arm of chromosome 5
(c) trisomy of $21^{s t}$ chromosome
(d) fertilization of an XX egg by a normal Y-bearing sperm
Show Answer
Answer : a
Hints & Solution
(a) Cri-du-chat syndrome in humans is caused by the partial deletion of the short arm of chromosome no. 5. This child has abnormalities in his/her facial expressions, mental retardation, they speak and cry like that of cat, heart does not work properly.