Molecular Basis of Inheritance Question 95
95. A mutation at one base of the first codon, of a gene, produces a non-functional protein. Such a mutation is called
[1997]
(a) nonsense mutation
(b) missensemutation
(c) frameshift mutation
(d) reverse mutation
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Answer : b
Hints & Solution
(b) A mutation bringing about early stoppage of polypeptide formation is called nonsense mutation. Frame shift mutation is a type of gene mutation where the reading of codons is changed due to insertion or deletion of nucleotides.
