Molecular Basis of Inheritance Question 95

95. A mutation at one base of the first codon, of a gene, produces a non-functional protein. Such a mutation is called

[1997]

(a) nonsense mutation

(b) missensemutation

(c) frameshift mutation

(d) reverse mutation

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Answer : b

Hints & Solution

(b) A mutation bringing about early stoppage of polypeptide formation is called nonsense mutation. Frame shift mutation is a type of gene mutation where the reading of codons is changed due to insertion or deletion of nucleotides.