Molecular Basis of Inheritance Question 132
132. The okazaki fragments in DNA chain growth
[2007]
(a) polymerize in the $3^{\prime}$ - to - 5’ direction and forms replication fork
(b) prove semi-conservative nature of DNA replication
(c) polymerize in the $5^{\prime}$ - to - 3’ direction and explain 3’ - to - 5’ DNA replication
(d) result in transcription.
Show Answer
Answer : c
Hints & Solution
(c) Okazaki fragments in DNA are linked up by the enzyme DNA ligase. Replication always occurs in 5’ - 3’ direction. Okazaki fragments synthesised on 3’ - 5’ DNA template, join to form lagging strand.
