Molecular Basis of Inheritance Question 132

132. The okazaki fragments in DNA chain growth

[2007]

(a) polymerize in the $3^{\prime}$ - to - 5’ direction and forms replication fork

(b) prove semi-conservative nature of DNA replication

(c) polymerize in the $5^{\prime}$ - to - 3’ direction and explain 3’ - to - 5’ DNA replication

(d) result in transcription.

Show Answer

Answer : c

Hints & Solution

(c) Okazaki fragments in DNA are linked up by the enzyme DNA ligase. Replication always occurs in 5’ - 3’ direction. Okazaki fragments synthesised on 3’ - 5’ DNA template, join to form lagging strand.