Biomolecules Question 61
61. Transition state structure of the substrate formed during an enzymatic reaction is :
(a) permanent but unstable
(b) transient and unstable
(c) permanent and stable
(d) transient but stable
Show Answer
Answer : b
Hints & Solutions
(b) Transition state structure formed during an enzymatic reaction is transient and unstable. All chemical reactions must go through the transition state to form a product from a substrate molecule. The transition state is the state corresponding to the highest energy along the reaction coordinate. It has more free energy in comparison to the substrate or product; thus, it is the least stable state.
