Biomolecules Question 61

61. Transition state structure of the substrate formed during an enzymatic reaction is :

(a) permanent but unstable

(b) transient and unstable

(c) permanent and stable

(d) transient but stable

Show Answer

Answer : b

Hints & Solutions

(b) Transition state structure formed during an enzymatic reaction is transient and unstable. All chemical reactions must go through the transition state to form a product from a substrate molecule. The transition state is the state corresponding to the highest energy along the reaction coordinate. It has more free energy in comparison to the substrate or product; thus, it is the least stable state.