Biomolecules Question 59
59. Select the option which is not correct with respect to enzyme action:
[2014]
(a) Substrate binds with enzyme at its active site.
(b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
(c) A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
(d) Malonate is a competitive inhibitor of succinic dehydrogenase.
Show Answer
Answer : b
Hints & Solutions
(b) Inhibitions of succinic dehydrogenase by malonate is an example of competitive inhibition. Thus it is a reversible reaction. On increasing the substrate (succinate) concentration the effect of inhibitor is removed and Vmax remains same.
