Biomolecules Question 59

59. Select the option which is not correct with respect to enzyme action:

[2014]

(a) Substrate binds with enzyme at its active site.

(b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.

(c) A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.

(d) Malonate is a competitive inhibitor of succinic dehydrogenase.

Show Answer

Answer : b

Hints & Solutions

(b) Inhibitions of succinic dehydrogenase by malonate is an example of competitive inhibition. Thus it is a reversible reaction. On increasing the substrate (succinate) concentration the effect of inhibitor is removed and Vmax remains same.