Coordination Compounds 2 Question 1

####1. The compound used in the treatment of lead poisoning is (2019 Main, 12 April II)

(a) D-penicillamine

(b) desferrioxime-B

(c) cis-platin

(d) EDTA

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Solution:

  1. The compound used in the treatment of lead poisoning is EDTA. Medication occurs through chelation therapy. Calcium disodium ethylenediamine tetracetic acid chelates divalent metal ion such as $Pb^{2+}$ from plasma and interstitial body fluids.

The metal displaces $Ca$ and is chelated, mobilised and usually excreted. Less then $5 % CaNa _2$ EDTA is absorbed in the gastrointestinal tract and it possibly increases the absorption of $Pb$ present in the tract. Therefore, it is not recommended for oral use. It is usually given intravenously.



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