Coordination Compounds 2 Question 1
####1. The compound used in the treatment of lead poisoning is (2019 Main, 12 April II)
(a) D-penicillamine
(b) desferrioxime-B
(c) cis-platin
(d) EDTA
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Solution:
- The compound used in the treatment of lead poisoning is EDTA. Medication occurs through chelation therapy. Calcium disodium ethylenediamine tetracetic acid chelates divalent metal ion such as $Pb^{2+}$ from plasma and interstitial body fluids.
The metal displaces $Ca$ and is chelated, mobilised and usually excreted. Less then $5 % CaNa _2$ EDTA is absorbed in the gastrointestinal tract and it possibly increases the absorption of $Pb$ present in the tract. Therefore, it is not recommended for oral use. It is usually given intravenously.
