Coordination Compounds 2 Question 1

####1. The compound used in the treatment of lead poisoning is (2019 Main, 12 April II)

(a) D-penicillamine

(b) desferrioxime-B

(c) cis-platin

(d) EDTA

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Solution:

  1. The compound used in the treatment of lead poisoning is EDTA. Medication occurs through chelation therapy. Calcium disodium ethylenediamine tetracetic acid chelates divalent metal ion such as Pb2+ from plasma and interstitial body fluids.

The metal displaces Ca and is chelated, mobilised and usually excreted. Less then 5 EDTA is absorbed in the gastrointestinal tract and it possibly increases the absorption of Pb present in the tract. Therefore, it is not recommended for oral use. It is usually given intravenously.



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