Neet Solved Paper 2015 Question 54

Question: Which one of the following statements is incorrect?

Options:

A) A competitive inhibitor reacts reversibly with the enzyme to form an enzyme-inhibitor.

B) In competitive inhibition the inhibitor molecule is not chemically changed by the enzyme.

C) The competitive inhibitor does not affect the rate of breakdown of the enzyme-substrate complex.

D) The presence of the competitive inhibitor decreases the km of the enzyme for the substrate.

Show Answer

Answer:

Correct Answer: D

Solution:

  • Competitive inhibitor resembles closely with the substrate and competes for the active binding site of the enzyme. The presence of competitive inhibitor decreases the affinity of the substrate to binding site of the enzyme which results in increase of Michaelis Menten constant (km).