Principles of Inheritance and Variation Question 130
130. Barr body in human female is formed by
[1996]
(a) inactivation of paternal X-chromosome
(b) inactivation of maternal X-chromosome
(c) inactivation of both X-chromosomes
(d) inactivation of either the paternal or maternal X-chromosome
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Answer : d
Hints & Solution
(d) According to the principle of dosage compensation, one of the two $X$ chromosomes in a female is inactivated at random. The inactivated $X$ chromosome appears as the Barr body.
