Molecular Basis of Inheritance Question 90
90. What base is responsible for hot spots for spontaneous point mutations?
[1998]
(a) Adenine
(b) 5-bromouracil
(c) 5-methylcytosine
(d) Guanine
Show Answer
Answer : c
Hints & Solution
(c) The term “hot spots” was used by Benzer for the sites which are more mutable than other sites. Studies in 1978 revealed that 5 -methylcytosine residues occur at the position of each hot spot.
