Human Health and Diseases Question 94
94. HIV that causes AIDS, first starts destroying:
(a) Leucocytes
(b) Helper T- Lymphocytes
(c) Thrombocytes
(d) B- Lymphocytes
Show Answer
Answer : b
Hints & Solutions
(b) After infection, HIV starts to destroy the T-cells (T-helper lymphocytes). T cells are very important for the immune system. In the early stage of infection, the decline in numbers of $T$ cells is observed. Immunosuppression is caused due to HIV infection is a resultant of several factors including defective innate signalling pathways, increased viral replication and virus load, gradual loss of peripheral CD4 $+T$ cells and depletion of $T$ lymphocytes at mucosal sites that collectively lead to progressive immune deficiency results in AIDS.
