Body Fluids and Circulation Question 94
94. Sickle cell anaemia is characterised by
(a) Leukemia
(b) Polycythemia
(c) Mental retardation
(d) Haemolytic anaemia
Show Answer
Answer : d
Hints & Solutions
(d) In sickle cell anaemia, normal haemoglobin ( $HbA$ ) gets changed in denatured form of haemoglobin (HbS) in which the haemoglobin molecule’s configuration changes and it changes its shape, in low $O_2$ concentration unable to transport $O_2$ and $RBCs$ become sickle shaped. It is a genetic disease caused by the denaturation of haemoglobin, that is why it is known as hemolytic anaemia.
