Biotechnology and Its Applications Question 32

32. The first clinical gene therapy was given for treating

(a) chicken pox

(b) diabetes mellitus

(c) rheumatoid arthritis

(d) adenosine deaminase deficiency

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Answer : d

Hints & Solutions

(d) Gene therapy is an experimental technique that uses genes to treat or prevent disease. Adenosine deaminase deficiency, also called ADA deficiency or ADA-SCID is an autosomal recessive metabolic disorder that causes immunodeficiency. ADA deficiency is due to a lack of the enzyme adenosine deaminase. The first clinical gene therapy was given for treating adenosine deaminase deficiency. A four-year old girl became the first gene therapy patient on September 14, 1990 at the NIH Clinical Center.



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