Biotechnology and Its Applications Question 31
31. Which one of the following vectors is used to replace the defective gene in gene therapy?
(a) Ti plasmid
(b) Adenovirus
(c) Cosmid
(d) Ri plasmind
Show Answer
Answer : b
Hints & Solutions
(b) Adenovirus is non-enveloped dsDNA virus which cause respiratory diseases. Specific modifications on fibre proteins are used to target adenovirus to certain cell types, a major effort is made to limit hepatotoxicity and prevent multiple organ failure. Adenovirus is used as a vehicle to administer targeted therapy in the form of recombinant DNA or protein.
