Genetics and Evolution: Molecular Basis of Inheritance – 9
What do you mean by protien Synthesis
Which enzymes helps in charging og tRNA
Which codon is called initiation codon
What do you mean by StopCodon
What are the role of Ribosomes
Initiation of protien Synthesis
Bacterial Ribosome
Eukaryotic Ribosomes
Ribosomes
Initiator Factors
Steps of Initiation of prokaryotes
mRNA binds to the small subunit of the ribosome
Intiator tRNA binds to the mRNA through base pairing between the codon and anticodon
Steps of Initiation on Eukaryotes
Elongation of protien chain
Elongation occurs in three phase
graph TD;
A[Elongation occurs in three phases];
A --> B[Phase 1];
A --> C[Phase 2];
A --> D[Phase 3];
B --> E[Details of Phase 1];
C --> F[Details of Phase 2];
D --> G[Details of Phase 3];
Delivery of charged tRNA to the a site
graph TD;
A[Delivery of charged tRNA to the A site] --> B[Step 1: Binding of tRNA to A site];
B --> C[Step 2: Peptide bond formation];
C --> D[Step 3: Translocation];
D --> E[Step 4: Release of uncharged tRNA];
E --> F[Step 5: Binding of new charged tRNA];
F --> G[Step 6: Repeat process until stop codon is reached];
Termination of protien Synthesis
graph TD;
A[Termination of Protein Synthesis];
A --> B1[Release Factor];
B1 --> C1[RF1];
B1 --> C2[RF2];
B1 --> C3[RF3];
A --> B2[Stop Codon];
B2 --> C4[UAA];
B2 --> C5[UAG];
B2 --> C6[UGA];
A --> B3[Peptidyl Transferase];
B3 --> C7[Hydrolysis];
A --> B4[Post Termination];
B4 --> C8[Ribosome Recycling];
B4 --> C9[Protein Folding];
Deconstruction of ribosomal complex
graph TD;
A[Deconstruction of Ribosomal Complex];
B[Subunit Separation];
C[Ribosomal Proteins];
D[Ribosomal RNAs];
E[Associated Factors];
A-->B;
A-->C;
A-->D;
A-->E;
B-->F[Initiation Factors];
B-->G[Translocation Factors];
C-->H[Protein Synthesis];
C-->I[Protein Folding];
D-->J[RNA Synthesis];
D-->K[RNA Folding];
E-->L[Energy Consumption];
E-->M[Regulation];
