Biomolecules and Chemistry in Everyday Life - Result Question 13

####13. The correct sequence of amino acids present in the tripeptide given below is

(2019 Main, 9 Jan II)

(a) Thr - Ser - Leu

(b) Leu - Ser - Thr

(c) Val - Ser - Thr

(d) Thr - Ser - Val

14 The increasing order of pKa of the following amino acids in] aqueous solution is Gly, Asp, Lys, Arg

(2019 Main, 9 Jan I)

(a) Asp < Gly < Arg < Lys

(b) Arg < Lys < Gly < Asp

(c) Gly < Asp < Arg < Lys

(d) Asp < Gly < Lys < Arg

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Answer:

Correct Answer: 13. (b)

Solution:

  1. Formation of the tripeptide (Val-Ser-Thr) can be shown as:

14 Amino acid molecules can be represented as,

Nature of the ’ R ’ group will determine the basicity (hence, pKa ) of an amino acid.

R ’ in the amino group Nature
of R
Nature of
the amino
acids
1. (CH2)3NHC/N+NH2(Arginine : Arg) 
(Argin
Basic More basic (due
to the presence
of acetamidine
group)
2. CH2CO//O
(Aspartic acid: Asp)
Acidic Acidic
3. —H (Glycine) : Gly Neutral Neutral
4. (CH2)4N+H3
(Lysine : Lys)
Basic Basic


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