Organic-Chemistry-Some-Basic-Principles-And-Techniques-Lecture-1-By-Prof-S-Sankararaman
1. Hybridization:
- sp³ hybridization: Tetrahedral geometry (e.g., alkane carbon atoms).
- sp² hybridization: Trigonal planar geometry (e.g., alkene carbon atoms).
- sp hybridization: Linear geometry (e.g., alkyne carbon atoms).
2. Resonance Structures:
- Understand how to draw resonance structures for molecules with delocalized electrons.
3. IUPAC Nomenclature:
- Learn the rules for naming organic compounds, including alkanes, alkenes, alkynes, and functional groups.
4. Isomerism:
- Structural Isomerism: Compounds with the same molecular formula but different connectivity.
- Stereoisomerism: Compounds with the same connectivity but different spatial arrangements (e.g., cis-trans isomerism in alkenes).
5. Reaction Mechanisms:
- Understand key reaction mechanisms, such as nucleophilic substitution (SN1 and SN2), elimination (E1 and E2), and addition reactions (e.g., Markovnikov and anti-Markovnikov additions).
6. Electrophiles and Nucleophiles:
- Electrophiles are electron-deficient species that attract electrons (e.g., carbocations).
- Nucleophiles are electron-rich species that donate electrons (e.g., nucleophilic atoms or groups).
7. Acid-Base Chemistry:
- Understand Bronsted-Lowry acid-base theory.
- Know common organic acids and bases (e.g., HCl, NH₄⁺, etc.).
8. Alkane Reactions:
- Combustion: Alkanes burn in the presence of oxygen to produce carbon dioxide and water.
- Halogenation: Alkanes react with halogens (e.g., Cl₂) in the presence of light to form alkyl halides.
9. Alkene Reactions:
- Addition Reactions: Understand addition reactions to alkenes (e.g., hydrogenation, halogenation, hydration, etc.).
10. Alkyne Reactions:
- Acidity of Alkynes: Alkynes are more acidic than alkanes and alkenes.
- Addition Reactions: Understand addition reactions to alkynes (e.g., hydrogenation, halogenation, hydration, etc.).
11. Functional Groups:
- Recognize common functional groups such as alcohols, aldehydes, ketones, carboxylic acids, esters, amides, etc.
12. Markovnikov’s Rule:
- In addition reactions to alkenes and alkynes, the hydrogen atom attaches to the carbon atom with more hydrogen substituents.
13. Reaction Conditions:
- Know the conditions (e.g., temperature, reagents, catalysts) required for specific reactions.
14. Stereochemistry:
- Learn about chiral and achiral compounds, enantiomers, diastereomers, and optical activity.
15. Organic Reagents:
- Familiarize yourself with common organic reagents, such as reducing agents (e.g., LiAlH₄), oxidizing agents (e.g., KMnO₄), and catalysts (e.g., Pt, Pd, Ni).
16. Spectroscopy:
- Understand the basics of Nuclear Magnetic Resonance (NMR) spectroscopy, Infrared (IR) spectroscopy, and Mass Spectrometry (MS) for compound analysis.
17. Reaction Mechanisms:
- Study reaction mechanisms for various reactions, including nucleophilic substitution, elimination, addition, and more.
18. Aromaticity:
- Know the criteria for aromaticity, such as the Huckel rule.
19. E-Z Isomerism:
- Understand the E-Z (cis-trans) notation for geometric isomerism in alkenes.
20. Reagents and Conditions Table:
- Create a table summarizing important reactions, reagents, and conditions for quick reference.