Example $\rightarrow$
** 1.** How many six digit natural numbers can be formed whose fifth and third digit is odd are remaining digits are even. (assume 0 is even)
Solution: The first digit is even $\rightarrow 2,4,6,8$
$\rightarrow$ (4 ways)
The second, fourth and sixth digits each can be from either of $\{0,2,4,6,8\} \rightarrow 5 \times 5 \times 5$ ways
The third and fifth digit each can be either ${1, 3,5,7,9} \rightarrow(5 \times 5)$ ways.
So total number of such 6-digit numbers is $4 \times 5^5$ $=12500$