chemistry-class-12-unit-14-chapter-09-biomolecules-l-9-12-uaq25fc5gt0

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Tertiary structure</B></primary></p>
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<p>It is a three dimensional arrangement of all atoms in the protein</p>
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<p>Protein folds spontaneously in the solution to maximize their stability</p>
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<p>Every time there is stablizing interactions between atoms, that releases free energy</p>
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<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/f40e4f3d-5f64-4735-fdcb-19b9b8f3f400/public" width="50%">

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<footer style="font-size:18px;"> <span style="color:blue">Tertiary structure</span> $\rightarrow$ Stabilizing interactions $\rightarrow$ Structure of protein $\rightarrow$ Globular protein $\rightarrow$ Quaternary structure $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Stabilizing interactions</B></primary></p>
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<p>Disulfide bonds</p>
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<p>Hydrogen bonds</p>
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<p>Electrostatic attractions</p>
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<p>Hydrophobic interaction</p>
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<p>Tertiary structure gives a specific overall shape to the protein</p>
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<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/1604cbf3-7b04-41f9-0063-5fc225ff2200/public" width="80%">

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<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ <span style="color:blue">Stabilizing interactions</span> $\rightarrow$ Structure of protein $\rightarrow$ Globular protein $\rightarrow$ Quaternary structure $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Stabilizing interactions</B></primary></p>
<hr>
<main>
<div style='float: left; width:60%;font-size:22px;text-align:left'>
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<p>It involves interaction and cross links between different part of the peptide chain</p>
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<p>Hydrophobic interaction-$H_3C{-}CH_3$</p>
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<li>Hydrophilic interactions</li>
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<p>Salt bridges</p>
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<p>Hydrogen bonds</p>
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<p>Disulfide bridges $\ S-S$</p>
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<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/1973ce66-5b39-4d22-01e0-5ea9ae776500/public" width="40%">

</div>
</main>
<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ <span style="color:blue">Stabilizing interactions</span> $\rightarrow$ Structure of protein $\rightarrow$ Globular protein $\rightarrow$ Quaternary structure $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Structure of protein</B></primary></p>
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<div style='float: left; width:60%;font-size:22px;text-align:left'>
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<p>$\alpha$ helix</p>
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<p>Salt bridge</p>
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<p>Disulfide bonds</p>
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<p>Hydrogen bonding</p>
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<p>Hydrophilic interaction to water</p>
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<p>Hydrophobic interaction</p>
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<p>$\beta$ pleated sheets</p>
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<div style='float: right; width:40%;'>
<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/b226bc05-8f76-4f8c-d84d-43917e13a300/public" width="80%">

</div>
</main>
<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ Stabilizing interactions $\rightarrow$ <span style="color:blue">Structure of protein</span> $\rightarrow$ Globular protein $\rightarrow$ Quaternary structure $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Globular protein</B></primary></p>
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<p><strong>Myoglobin</strong></p>
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<p>Synthesis, transport and metabolism in the cells</p>
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<p><strong>Fibrous protein</strong> - consist of long fiber like shapes eg. $\alpha$-keratins ${-}$ hair, wool, skin and nails</p>
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<p>Feathers contain $\beta$-keratins with large amount of $\beta$- pleated sheet structure</p>
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<p><img alt="image" src="/subject-images/iitpal/image/chemistry-class-12-unit-14-chapter-09-biomolecules-l-9_12-uaq25fc5gt0-207-1590.0.jpg"></p>
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</main>
<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ Stabilizing interactions $\rightarrow$ Structure of protein $\rightarrow$ <span style="color:blue">Globular protein</span> $\rightarrow$ Quaternary structure $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Quaternary structure</B></primary></p>
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<main>
<div style='float: left; width:60%;font-size:22px;text-align:left'>
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<p>$\alpha$ keratin $\rightarrow \alpha$ helix</p>
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<p><strong>Quaternary structure</strong></p>
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<p>Some proteins have more than one polypeptide chain. The individual chains are called subunit</p>
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<p>A protein with a single subunits is called a monomer</p>
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<p>With two subunits ${-}$ dimer</p>
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<p>Three subunits ${-}$ trimer</p>
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<p>Four subunits ${-}$ tetramer</p>
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<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/81380381-4414-42ec-2003-ff747fa2fe00/public" width="70%">

</div>
</main>
<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ Stabilizing interactions $\rightarrow$ Structure of protein $\rightarrow$ Globular protein $\rightarrow$ <span style="color:blue">Quaternary structure</span> $\rightarrow$ Hemoglobin </footer>

<p><Success style="float:center;text-align:center;font-size:28px;"> <B>Biomolecules Lecture-9</B></Success></p>
<p><primary style="float:center;text-align:center;font-size:24px;"> <B>Haemoglobin</B></primary></p>
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<main>
<div style='float: left; width:60%;font-size:22px;text-align:left'>
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<p>Hemoglobin- It is a tetramer</p>
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<p>The subunits of a protein are held together by the same kinds of interactions Haemoglobin that hold the individual protein chains in a particular three- dimensional conformation</p>
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<p>Hydrophobic interaction, hydrogen bonding, and electrostatic  attractions</p>
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<div style='float: right; width:40%;'>
<img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/05a451ca-e1b7-4862-d0d8-13498ac5d100/public" width="80%">

</div>
</main>
<hr>
<footer style="font-size:18px;"> Tertiary structure $\rightarrow$ Stabilizing interactions $\rightarrow$ Structure of protein $\rightarrow$ Globular protein $\rightarrow$ Quaternary structure $\rightarrow$ <span style="color:blue">Hemoglobin</span> </footer>