Biomolecules Lecture-7
Amino acids
Aliphatic side chain amino acids
Acidic amino acids
Amino acids with benzene ring
Hetrocyclic amino acids
Configuration of amino acids
Acid-base properties of amino acids
The isoelectric point
The isoelectric point of an amino acid is the pH at which it has no net charge
In other words, it is the pH at which the amount of positive charge on an amino acid exactly balances the amount of (-) ve charge
pI = pH at which there is no net charge
Determining the pI
An introduction to protein structure
The primary structure of a protein is the sequence the amino acids in the chain and the location of all the disulfide bridges
Secondary structures are regular conformations assumed by segments of the protein’s backbone when it folds
Tertiary structure
The tertiary structure is the three dimensional structure of entire protein
If a protein has more than one polypeptide chain, it also has a quaternary structure
The quaternary structure is the way the individual polypeptide chains are arranged with respect to one another
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