Chemistry in everyday life - What is biological response

  • Introduction to biological response
  • Definition of biological response
  • Importance of studying biological response
  • Examples of biological responses
    • Heart rate increase during exercise
    • Pupil dilation in response to light
    • Adrenaline release during stressful situations
  • Mechanisms of biological response
  • Key molecules involved in biological response
  • Relevance of chemical substances in biological response
  • Effects of biological response on human health
  • Applications of understanding biological response in medicine
  1. Mechanisms of biological response
  • Signal transduction pathways
  • Receptor-ligand interactions
  • Activation of cellular pathways
  • Secondary messengers
  • Amplification of signals
  1. Key molecules involved in biological response
  • Proteins and enzymes
  • Hormones
  • Neurotransmitters
  • Receptors
  • Signaling molecules
  1. Relevance of chemical substances in biological response
  • Drugs and their effects on biological responses
  • Environmental pollutants and their impact on biological responses
  • Natural products and their role in physiological responses
  • Chemical reactions and their influence on biological processes
  • Synthetic chemicals and their potential disruptors of biological responses
  1. Effects of biological response on human health
  • Regulation of metabolic pathways
  • Maintenance of homeostasis
  • Immune response and inflammation
  • Genetic inheritance and variations in biological responses
  • Impact of malfunctioning biological responses on diseases
  1. Applications of understanding biological response in medicine
  • Drug development and testing
  • Targeted therapies based on specific biological responses
  • Diagnosis and monitoring of diseases through biomarkers
  • Pharmacogenomics and personalized medicine
  • Understanding the role of biological responses in drug resistance
  1. Examples of biological response
  • Vasodilation and vasoconstriction in response to temperature changes
  • Release of endorphins in response to pain or exercise
  • Insulin secretion in response to high blood sugar levels
  • Allergic reaction to allergens
  • Production of antibodies in response to infections
  1. Heart rate increase during exercise
  • Mechanism of increased heart rate during physical activity
  • Role of adrenaline and noradrenaline in increasing heart rate
  • Importance of increased blood flow during exercise
  • Regulation of heart rate through the autonomic nervous system
  1. Pupil dilation in response to light
  • Role of the iris in controlling pupil size
  • Mechanism of pupil dilation in response to increased light intensity
  • Importance of pupil dilation for better vision in low light conditions
  • Regulation of pupil size through the autonomic nervous system
  1. Adrenaline release during stressful situations
  • Role of the adrenal glands in producing adrenaline
  • Mechanism of adrenaline release during stress
  • Physiological changes associated with adrenaline release (increased heart rate, heightened senses)
  • Fight or flight response and its significance in survival
  1. Regulation of metabolic pathways
  • Role of enzymes in catalyzing metabolic reactions
  • Feedback inhibition and allosteric regulation of metabolic pathways
  • Importance of maintaining metabolic homeostasis
  • Examples of metabolic disorders and their impact on biological responses
  • Impact of drugs and toxins on metabolic pathways
  1. Types of chemical reactions in biology
  • Oxidation-reduction reactions (redox)
    • Role of electron transfer in redox reactions
    • Examples of redox reactions in biological systems (cellular respiration, photosynthesis)
  • Acid-base reactions
    • Importance of maintaining pH balance in biological systems
    • Buffer solutions and their role in regulating pH
  • Hydrolysis reactions
    • Breakdown of macromolecules into smaller subunits
    • Examples of hydrolysis reactions (digestion of food, breakdown of ATP)
  • Condensation reactions
    • Formation of larger molecules from smaller subunits
    • Importance of condensation reactions in synthesis of proteins, nucleic acids
  1. Enzymes in biological reactions
  • Definition of enzymes and their role in catalysis
  • Activation energy and enzyme-catalyzed reactions
  • Lock and key model vs. induced fit model
  • Factors affecting enzyme activity
    • Temperature and pH
    • Substrate concentration
    • Enzyme inhibitors
  1. Examples of enzymes and their biological roles
  • Amylase: hydrolysis of starch into glucose
  • DNA polymerase: synthesis of DNA during replication
  • Catalase: breakdown of hydrogen peroxide
  • Lipase: hydrolysis of lipids into fatty acids and glycerol
  • Protease: hydrolysis of proteins into amino acids
  1. Hormones and their role in biological responses
  • Definition of hormones and their function
  • Classification of hormones (steroid, peptide, amine)
  • Examples of hormones and their specific roles
    • Insulin: regulation of glucose levels in the blood
    • Thyroxine: regulation of metabolism
    • Adrenaline: response to stress
    • Estrogen and progesterone: regulation of the reproductive system
  1. Role of neurotransmitters in biological responses
  • Definition of neurotransmitters and their function
  • Types of neurotransmitters (dopamine, serotonin, acetylcholine)
  • Significance of neurotransmitters in communication between neurons
  • Neurotransmitter imbalances and their impact on mental health
  1. Receptors and their role in biological responses
  • Definition of receptors and their function
  • Types of receptors (ion channels, G protein-coupled receptors, enzyme-linked receptors)
  • Ligand-receptor interactions and signal transduction
  • Examples of receptor-ligand interactions and their biological effects
  1. Signaling molecules in biological responses
  • Definition of signaling molecules (hormones, neurotransmitters)
  • Autocrine, paracrine, and endocrine signaling
  • Cellular response to signaling molecules
  • Examples of important signaling molecules and their roles (epinephrine, serotonin, insulin)
  1. Impact of biological responses on human health
  • Maintenance of physiological balance and homeostasis
  • Regulation of immune response and inflammation
  • Genetic variations and their influence on biological responses
  • Dysfunction of biological responses in diseases (diabetes, allergies, autoimmune disorders)
  1. Pharmacogenomics and personalized medicine
  • Relationship between genetics and drug response
  • Role of pharmacogenomics in tailoring drug treatments to individuals
  • Prediction of drug efficacy and potential side effects
  • Advantages and challenges of personalized medicine
  1. Conclusion and recap
  • Importance of understanding biological responses in everyday life
  • Relevance of chemistry in studying biological responses
  • Recap of key concepts discussed in the lecture
  • Application of knowledge in future studies and career paths