Biomolecules Double Helix
Biomolecules - Double helix
Introduction to double helix
Structure of DNA
Composed of nucleotides
Sugar-phosphate backbone
Nitrogenous bases (adenine, thymine, guanine, cytosine)
Biomolecules Double Helix
Base pairing rule and Importance of Double Helix
Base pairing rule
Adenine with thymine
Guanine with cytosine
Complementary strand formation
DNA replication process
Importance of double helix in heredity
Examples of DNA structure in real-life applications
DNA profiling in forensic science
Genetic engineering
Biomolecules Double Helix
Importance of Double Helix in Heredity
Double helix structure of DNA allows for the accurate transmission of genetic information from one generation to the next
DNA replication ensures that each new cell produced during cell division receives an exact copy of the genetic material
Through DNA replication, the information encoded in the DNA molecule is preserved and passed on to offspring
Double helix structure also allows for the potential of genetic variation through mechanisms such as genetic recombination and mutations
Biomolecules Double Helix
Examples of DNA Structure in Real-Life Applications - DNA Profiling
DNA profiling, also known as DNA fingerprinting, utilizes the unique DNA sequence variations between individuals to identify and differentiate them
The double helix structure of DNA allows for the extraction and analysis of DNA from various biological samples (e.g., blood, hair, saliva, etc.) in forensic investigations
DNA profiling has been instrumental in solving crime cases, establishing paternity/maternity, and exonerating the wrongly accused
Biomolecules Double Helix
Examples of DNA Structure in Real-Life Applications - Genetic Engineering
The ability to manipulate the structure and function of DNA is essential in genetic engineering techniques
Through recombinant DNA technology, scientists can introduce new genetic material into an organism’s DNA, creating genetically modified organisms (GMOs)
Manipulating the double helix structure allows for the insertion, deletion, or modification of specific genes, leading to desired traits or characteristics in the organism
Examples of genetic engineering applications include agricultural biotechnology (improving crop traits), medical biotechnology (producing therapeutic proteins), and environmental biotechnology (bioremediation)
Biomolecules Double Helix
Bioinformatics and Genomic Studies
Bioinformatics is the interdisciplinary field that combines biology, computer science, and mathematics to analyze and interpret biological data, particularly genomic information
The double helix structure of DNA provides the foundation for genomic studies
With advances in DNA sequencing technologies, vast amounts of genomic data can be generated and analyzed
Bioinformatics tools and algorithms allow scientists to compare DNA sequences, identify genes, predict protein structures and functions, and understand the relationships between DNA, genes, and diseases
Biomolecules Double Helix
Summary of the Double Helix Structure
The double helix structure is a fundamental characteristic of DNA
It consists of two antiparallel strands of nucleotides held together by hydrogen bonds between the complementary nitrogenous bases
Adenine pairs with thymine, and guanine pairs with cytosine, following the base pairing rule
The double helix structure plays a vital role in heredity, DNA replication, and various applications in different fields of science
Biomolecules Double Helix
Carbohydrates
Introduction to carbohydrates
Classification of carbohydrates based on size and structure
Monosaccharides
Disaccharides
Oligosaccharides
Polysaccharides
Functions of carbohydrates in living organisms
Biomolecules Double Helix
Examples of carbohydrates
Glucose
Sucrose
Starch
Cellulose
Reactions of carbohydrates
Hydrolysis
Dehydration synthesis
Biomolecules Double Helix
Proteins
Introduction to proteins
Structure and composition of proteins
Amino acids as building blocks
Peptide bonds
Classification of proteins based on structure and function
Primary, secondary, tertiary, and quaternary structures
Enzymes, antibodies, hormones, structural proteins, etc.
Functions of proteins in living organisms
Biomolecules Double Helix
Examples of proteins
Hemoglobin
Insulin
Collagen
Proteins as catalysts (enzymes) and their role in metabolic reactions
Denaturation of proteins and its impact on their structure and function
Biomolecules Double Helix
Lipids
Introduction to lipids
Classification of lipids
Fatty acids
Triglycerides
Phospholipids
Steroids
Structure and properties of lipids
Functions of lipids in living organisms
Biomolecules Double Helix
Examples of lipids
Saturated and unsaturated fatty acids
Phospholipids in cell membranes
Cholesterol
Role of lipids in energy storage and insulation
Importance of lipids in human nutrition
Biomolecules Double Helix
Nucleic Acids
Introduction to nucleic acids
Structure and composition of nucleic acids
Nucleotides as building blocks
Sugar-phosphate backbone
Nitrogenous bases (adenine, thymine, guanine, cytosine, uracil)
Types of nucleic acids
DNA (deoxyribonucleic acid)
RNA (ribonucleic acid)
Functions of nucleic acids in living organisms
Biomolecules Double Helix
Examples of nucleic acids
DNA as the carrier of genetic information
mRNA in protein synthesis
Role of nucleic acids in heredity and gene expression
Nucleic acid sequencing and its significance in genomics research
Biomolecules Double Helix
Enzymes
Introduction to enzymes
Characteristics of enzymes
Biological catalysts
Specificity and selectivity
Factors affecting enzyme activity
Temperature, pH, substrate concentration
Enzyme inhibitors
Biomolecules Double Helix
Enzyme kinetics and applications
Michaelis-Menten equation
Enzyme-substrate complex formation
Rate of reaction and turnover number
Industrial and medical applications of enzymes
Food industry (e.g., fermentation)
Pharmaceuticals (enzyme drugs)
Enzyme regulation and allosteric control
Biomolecules Double Helix
Acids and Bases
Introduction to acids and bases
Definitions of acids and bases
Arrhenius definition
Brønsted-Lowry definition
Strength and concentration of acids and bases
pH scale and calculations
Biomolecules Double Helix
Acid-base indicators
Common acids and their uses
Hydrochloric acid, sulfuric acid, acetic acid
Common bases and their uses
Sodium hydroxide, ammonia, calcium hydroxide
Acid-base neutralization reactions and their applications
Biomolecules Double Helix
Redox Reactions
Introduction to redox reactions
Definitions of oxidation and reduction
Redox reactions involving electron transfer
Oxidation states and assigning them in compounds
Balancing redox reactions using the half-reaction method
Redox reactions in electrochemical cells
Applications of redox reactions
Batteries and fuel cells
Corrosion prevention
Oxidation-reduction titrations
Biomolecules Double Helix
Chemical Kinetics
Introduction to chemical kinetics
Factors affecting reaction rate
Concentration, temperature, catalysts
Rate laws and reaction orders
Determining reaction orders from experimental data
Rate constants and their significance
Rate-determining step
Collision theory and activation energy
Reaction mechanisms
Applications of chemical kinetics in industry and medicine
Biomolecules Double Helix
Equilibrium
Introduction to chemical equilibrium
The concept of reversible reactions
Equilibrium constant (K)
Expressions and calculations
Le Chatelier’s principle
Factors affecting equilibrium position
Temperature, pressure, concentration
Solubility equilibrium
Acid-base equilibrium
Industrial applications of equilibrium principles
Haber-Bosch process (ammonia synthesis)
Contact process (sulfuric acid production)
Biomolecules Double Helix
Organic Chemistry
Introduction to organic chemistry
Unique properties of carbon atoms
Structure and bonding in organic compounds
Functional groups and their characteristics
Isomerism in organic compounds
Nomenclature of organic compounds
Reactions and reaction mechanisms in organic chemistry
Importance of organic compounds in everyday life
Pharmaceuticals, polymers, fuels, etc.
Carbon-based compounds in environmental issues