Slide 1
Biomolecules - Lengthening of Chain
- All biomolecules are composed of long chains of smaller units.
- Lengthening of the chain can occur through polymerization reactions.
- Biomolecules can be linear or branched depending on the type of bonding.
Slide 2
Linear Biomolecules
- Linear biomolecules have a straight chain structure.
- Carbohydrates and proteins can have linear arrangements.
- Examples: glucose, sucrose, and glycine.
Slide 3
Branched Biomolecules
- Branched biomolecules have side chains attached to the main chain.
- Lipids and nucleic acids can have branched arrangements.
- Examples: triglycerides and DNA.
Slide 4
Polymerization Reactions
- Polymerization reactions join smaller units (monomers) to form longer chains (polymers).
- Two types of polymerization reactions:
- Addition polymerization: Monomers join without the elimination of any byproduct.
- Condensation polymerization: Monomers join with the elimination of a small molecule.
Slide 5
Addition Polymerization
- Involves the repetition of an unsaturated monomer unit.
- Monomers add to the growing polymer chain.
- Examples: polyethylene, polystyrene.
Slide 6
Condensation Polymerization
- Involves the reaction between two different monomer units.
- Monomers combine while eliminating a small molecule (usually water).
- Examples: nylon, polyester.
Slide 7
Carbohydrates
- Organic compounds consisting of carbon, hydrogen, and oxygen.
- Classified into three main types: monosaccharides, disaccharides, and polysaccharides.
- Main functions include energy storage and providing structural support.
Slide 8
Monosaccharides
- Simplest carbohydrates, also called simple sugars.
- Contain a single sugar unit.
- Examples: glucose, fructose.
Slide 9
Disaccharides
- Carbohydrates formed by the joining of two monosaccharide units.
- Joined by a glycosidic bond formed through condensation reaction.
- Examples: sucrose, lactose.
Slide 10
Polysaccharides
- Complex carbohydrates composed of many monosaccharide units.
- Functions include energy storage and providing structural support.
- Examples: starch, cellulose, glycogen.
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Slide 11
Proteins
- Complex biomolecules composed of amino acids.
- Essential for growth, repair, and maintenance of body structures.
- Functions include enzyme catalysis, transport, and immune response.
Slide 12
Amino Acids
- Building blocks of proteins.
- Composed of an amino group, carboxyl group, and a side chain.
- Exist in both acidic and basic forms.
- Examples: glycine, alanine, lysine.
Slide 13
Protein Structure
- Proteins have a hierarchical structure.
- Primary structure: sequence of amino acids.
- Secondary structure: regular folding patterns (alpha helix, beta sheet).
- Tertiary structure: overall 3D structure.
- Quaternary structure: arrangement of multiple protein subunits.
Slide 14
Enzymes
- Specialized proteins that catalyze biochemical reactions.
- Increase the rate of reaction without being consumed.
- Enzyme-substrate complex forms during reaction.
- Specificity is determined by the enzyme’s active site.
Slide 15
Lipids
- Biomolecules that include fats, oils, and waxes.
- Composed of carbon, hydrogen, and oxygen.
- Functions include energy storage, insulation, and cell membrane structure.
Slide 16
Fatty Acids
- Building blocks of lipids.
- Consist of a carboxyl group attached to a hydrocarbon chain.
- Can be saturated (no double bonds) or unsaturated (double bonds present).
- Examples: palmitic acid, oleic acid.
Slide 17
Triglycerides
- Most common form of dietary lipids.
- Composed of glycerol and three fatty acid molecules.
- Functions as energy storage in adipose tissue.
- Examples: vegetable oils, butter.
Slide 18
Phospholipids
- Major component of cell membranes.
- Composed of glycerol, two fatty acid chains, and a phosphate group.
- Amphipathic molecules with hydrophilic and hydrophobic regions.
Slide 19
Nucleic Acids
- Biomolecules involved in the storage and transmission of genetic information.
- Composed of nucleotide monomers.
- Two main types: DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Slide 20
Nucleotides
- Building blocks of nucleic acids.
- Composed of a sugar (ribose or deoxyribose), a phosphate group, and a nitrogenous base.
- Four types of nitrogenous bases: adenine, guanine, cytosine, thymine or uracil (in RNA).
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Slide 21
Lipids - Types and Functions
- Triglycerides are the main storage form of lipids in the body.
- Phospholipids are major components of cell membranes.
- Steroids play a role in hormone production and cell signaling.
- Lipids function as insulation, energy storage, and protection of organs.
Slide 22
Lipids - Saturated vs Unsaturated
- Saturated fats have no double bonds between carbon atoms.
- Unsaturated fats have one or more double bonds.
- Saturated fats are solid at room temperature, while unsaturated fats are liquid.
- Examples of saturated fats: butter, coconut oil.
- Examples of unsaturated fats: olive oil, avocado.
Slide 23
Nucleic Acids - DNA vs RNA
- DNA (deoxyribonucleic acid) stores genetic information.
- RNA (ribonucleic acid) helps in protein synthesis.
- DNA is double-stranded, while RNA is single-stranded.
- DNA has the bases: adenine, guanine, cytosine, and thymine.
- RNA has the bases: adenine, guanine, cytosine, and uracil.
Slide 24
Nucleic Acids - Structure of Nucleotides
- Nucleotides consist of a sugar (ribose or deoxyribose), a phosphate group, and a nitrogenous base.
- Phosphate group forms the backbone of the nucleotide chain.
- Sugar can be either ribose or deoxyribose.
- Nitrogenous base determines the type of nucleotide.
- Examples of nucleotides: ATP (adenosine triphosphate), DNA, RNA.
Slide 25
DNA - Double Helix Structure
- DNA has a double helix structure.
- Complementary base pairing occurs between adenine (A) and thymine (T), and between guanine (G) and cytosine (C).
- Hydrogen bonds form between the base pairs.
- The two strands are antiparallel, running in opposite directions.
Slide 26
RNA - Types and Functions
- Three types of RNA: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA).
- mRNA carries genetic information from DNA to the ribosome.
- tRNA transports amino acids to the ribosome during protein synthesis.
- rRNA is a structural component of the ribosome.
Slide 27
RNA - Transcription and Translation
- Transcription is the process of synthesizing mRNA from DNA.
- In transcription, RNA polymerase binds to a specific promoter region and unwinds the DNA helix.
- Translation is the process of protein synthesis using the mRNA code.
- It occurs at the ribosome using tRNA and rRNA.
Slide 28
RNA - Central Dogma of Molecular Biology
- Central Dogma: DNA is transcribed into RNA, which is then translated into protein.
- DNA replication occurs prior to cell division.
- Transcription and translation are essential processes for protein synthesis.
- Errors in these processes can result in genetic disorders.
Slide 29
Biomolecules - Importance in Living Organisms
- Biomolecules are essential for the structure, function, and regulation of living organisms.
- Carbohydrates provide energy and structural support.
- Proteins perform various functions, including enzyme catalysis and transport.
- Lipids are important for energy storage and cell membrane integrity.
- Nucleic acids store and transmit genetic information.
Slide 30
Summary
- Biomolecules are made up of long chains of smaller units.
- Polymerization reactions can lengthen these chains through addition or condensation reactions.
- Carbohydrates, proteins, lipids, and nucleic acids are important biomolecules.
- Each biomolecule has unique functions and structures.
- Understanding biomolecules is crucial in studying the chemistry of living organisms.