<h4 id="successprotein-structure--engineering-part---2success"><Success>Protein structure & engineering (Part - 2)</Success></h4> </div> <div style='float: right; width:0%;'> <p><img alt="image" src="https://temp-public-img-folder.s3.ap-south-1.amazonaws.com/sathee.prutor.images/subject-images/iitpal/image/biology-class-12-unit-16-chapter-05-non-covalent-bonds-lecture-5_6-kjd4_8lyhts-025-0034.8.jpg"></p> </div>

<div> <h3 id="successproteinssuccess"><Success>Proteins</Success></h3> </div> <div style='float: left; width:50%;font-size:30px;text-align:left'> <ul> <li>Make up about 15% of the cell</li> <li>Have many functions in the cell</li> <li>Enzymes</li> <li>Storage</li> <li>Structural</li> <li>Receptors</li> <li>Motor</li> <li>Signaling</li> <li>Protection</li> <li>Transport</li> <li>Gene regulation</li> <li>Special functions</li> </ul> </div> <div style='float: right; width:50%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/8e68d42f-2423-4c80-eabe-b6c298492a00/public" width="100%"> <!----> </div>

<div> <h3 id="successproteinssuccess-1"><Success>Proteins</Success></h3> </div> <div style='float: left; width:100%;'> <img src= "https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/50dd7567-5908-4b08-dd4b-3fa3dec93500/public" style='width:100%'> <!----> <!--.jpg)--> </div> <!--<div style='float: right; width:50%;'>--> <!----> <!--.jpg)--> <!--</div>-->

<div> <h3 id="successproteinssuccess-2"><Success>Proteins</Success></h3> </div> <div style='float: right; width:100%;'> <img src= "https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/2c56ddac-b95b-4b8e-1fef-639d56d50600/public" style='width:100%'> <!----> <!----> </div>

<div> <h3 id="successproteinssuccess-3"><Success>Proteins</Success></h3> </div> <div style='float: right; width:100%;'> <img src= "https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/76838344-9a77-4318-4e6f-8f430b649a00/public" style='width:60%'> <!----> </div>

<div> <h3 id="successprotein-structuressuccess"><Success>Protein structures</Success></h3> </div> <div style='float: left; width:50%;font-size:25px;text-align:left'> <p><strong>Primary structure</strong></p> <ul> <li>Is simply the sequence of amino acids in a polypeptide chain.</li> <li><strong>Example-</strong> Insulin</li> <li><strong>Example-</strong> Hemoglobin- normal and sickle cell anemia form</li> </ul> </div> <div style='float: right; width:50%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/eae03ed5-57aa-466e-0064-2655d7c54c00/public" width="100%"> <!----> </div>

<div> <h3 id="successsecondary-structuresuccess"><Success>Secondary structure</Success></h3> </div> <div style='float: left; width:40%;font-size:30px;text-align:left'> <ul> <li>How the sequence is twisted or folded</li> <li>An alpha helix is coil of amino acids that are held in place by H-bonding</li> <li>Wool is a stretchy protein that is mostly alpha helix</li> </ul> </div> <div style='float: right; width:60%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/330d0554-7dc0-4764-eeb5-a1c9076bfd00/public" width="100%"> <!----> </div>

<div> <h3 id="successsecondary-structuresuccess-1"><Success>Secondary structure</Success></h3> </div> <div style='float: left; width:100%;font-size:30px;text-align:left'> <ul> <li>The beta pleated sheets consists of an extended chain of amino acids</li> <li>The Beta pleated sheets are placed in space by H-bonds between groups of adjacent chains</li> <li>Silk is a non-stretchy protein which is mostly beta pleated sheet</li> </ul> </div> <div style='float: right; width:0%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/af51baa7-0453-4925-212f-5be255e10400/public" width="100%"> <!----> </div>

<div> <h3 id="successtertiary-structuressuccess"><Success>Tertiary structures</Success></h3> </div> <div style='float: left; width:50%;font-size:30px;text-align:left'> <ul> <li>How the twisted chain is folded into a compact structure</li> <li>Tertiary structure is held in place by H- bonding and by many forces among various groups</li> <li>Non-polar groups tend to fold to the interior of the protein where polar groups assemble at the periphery</li> </ul> </div> <div style='float: right; width:50%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/448e18ba-54c7-4ee4-315f-328b24722000/public" width="100%"> <!----> </div>

<div> <h3 id="successquaternary-structuresuccess"><Success>Quaternary structure</Success></h3> </div> <div style='float: left; width:50%;font-size:30px;text-align:left'> <ul> <li>Many proteins are actually assemblies of multiple polypeptide chains. The quaternary structure refers to the number and arrangement of the protein subunits with respect to one another</li> <li>Examples Hemoglobin, DNA polymerase, and ion channels</li> </ul> </div> <div style='float: right; width:50%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/21fd18ad-7c8b-4ed9-9a70-996a3adefe00/public" width="100%"> <!----> </div>

<div> <h3 id="successinteresting-facts-about-proteinssuccess"><Success>Interesting facts about proteins</Success></h3> </div> <div style='float: right; width:100%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/3294ad97-8335-4d31-1f6d-f2feac4bc300/public" width="70%"> <!----> </div>

<div> <h3 id="successknotted-proteinssuccess"><Success>Knotted proteins</Success></h3> </div> <div style='float: right; width:100%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/9bb0f121-0625-4b36-d8aa-8af2ffa20700/public" width="70%"> <!----> </div>

<div> <h3 id="successprotein-foldingsuccess"><Success>Protein folding</Success></h3> </div> <div style='float: right; width:100%;'> <img src="https://imagedelivery.net/YfdZ0yYuJi8R0IouXWrMsA/03812da3-938f-4e78-ce38-f3f35e380900/public" width="100%"> <!----> </div>

<div> <h3 id="successthank-yousuccess"><Success>Thank you</Success></h3> </div> <div style='float: right; width:0%;'> <p><img alt="image" src="https://temp-public-img-folder.s3.ap-south-1.amazonaws.com/sathee.prutor.images/subject-images/iitpal/image/biology-class-12-unit-16-chapter-05-non-covalent-bonds-lecture-5_6-kjd4_8lyhts-427-3066.0.jpg"></p> </div>