Ans. (c)
Sol. Transmission of HIV-infection generally occurs by
(i) Sexual contact with infected person
(ii) Transfusion of contaminated blood and blood products.
(iii) Sharing infected needles as in the case of intravenous drug abusers
Sol. to be continued
(iv) Infected mother to her child through placenta.
Ques. ‘Smack’ is a drug obtained from the
(a) Latex of Papaver somniferum (b) Leaves of Cannabis sativa (c) Flowers of Dhatura pinata (d) Fruits of Erythroxyl coca
Ans. (a)
Sol. Heroin, commonly called smack, is chemically diacetyl morphine which is a white, odourless, bitter, crystalline compound.
Flower of Dhatura Active chemical of Dhatura flower is tropane alkaloids mainly scopolamines, hyoscyamine and atroplne.
Fruits of Erythroxyl coca Cocaine is extracted from the dried leaves and young twigs of Erythroxyl coca.
Ques. The substance produced by a cell in viral infection that can protect other cells from further infection is
(a) Serotonin (b) Colostrum (c) Interferon (d) Histamine
Thinking Process
Sol. The cytokine-barriers include interferons.
These are the proteins secreted by virus infected cells, which protect non-infected cells from further viral infection.
Serotonin It is a neurotransmitter that leads to depression.
Colostrum It is present in the lactating mother’s breast milk, contains antibodies which protect the newborn against disease.
Histamine Histamine is also a neurotransmitter involved in inflammatory response.
Ques. Transplantation of tissues/organs to save certain patients often fails due to rejection of such tissues/organs by the patient.
(a) Auto-immune response (b) Humoral immune response (c) Physiological immune response (d) Cell-mediated immune response
Ans. (d)
Sol. Transplantation is the replacement of a diseased organ or tissue of an individual with healthy organ or tissue of same or another individual.
Ques. Antibodies present in colostrum which protect the new born from certain diseases is of
(a) IgG type (b) IgA type (c) IgD type (d) IgE type
Ans. (b)
Sol. The yellowish fluidcolostrum is secreted by mother during the initial days of lactation has abundant antibodies ( $\operatorname{Ig} A)$ to protect the infant from several diseases.
Ques. Tobacco consumption is known to stimulate secretion of adrenaline and noradrenaline.
(a) Nicotine (b) Tannic acid (c) Curaimin (d) Catechine
Sol. Tobacco has nicotine, which stimulates the adrenal gland to release adrenaline and noradrenaline which in turn increases the blood pressure and heart rate, while tannic acid is a type of polyphenol used as a mordant, curaimin, obtained from cureumin in a pain releiver and catechine derived from catechu is an antioxidant.
Ques. Anti venom against snake poison contains
(a) Antigens (b) Antigen-antibody complexes (c) Antibodies (d) Enzymes
Sol. Snake antivenom is a biological product that typically consists of venom neutralising antibodies derived from a host animal, such as a horse or sheep, it is not considered as antigen or antigen-antibody complex or enzyme.
Ques. Which of the following is not a lymphoid tissue?
(a) Spleen (b) Tonsils (c) Appendix (d) Thymus
Sol. Lymphoid organs are the organs where origin and/or maturation and proliferation of lymphocytes occur.
The secondary lymphoid organs provide the sites for interaction of lymphocytes with the antigen, which then proliferate to becomes effector cells.
Appendix is sometime not considered as the lymphoid organ, as it has been proposed to be a vestigial structure connected to the cecum, located near the junction of the small intestine and the large intestine.
Ques. Which of the following glands is large sized at birth but reduces in size with ageing?
(a) Pineal (b) Pituitary (c) Thymus (d) Thyroid
Sol. The thymus is a lobed organ located near the heart and beneath the breastbone.
The thymus is quite large at the time of birth but keeps reducing in size with age and by the time puberty is attained it reduces to a very small size.
While the size of pineal gland (located at brain), pituitary gland (in brain), thyroid (located infront of neck) remains constant in size since birth.
Ques. Haemozoin is
(a) Precursor of haemoglobin (b) Toxin from Streptococcus (c) Toxin from Plasmodium species (d) Toxin from Haemophilus species
Sol. Haemozoin is a toxin released by Plasmodium species, which is responsible for the chill and high fever recurring every three to four days.
Ques. One of the following is not the causal organism for ringworm
(a) Microsporum (b) Trichophyton (c) Epidermophyton (d) Macrosporum
Sol. Ringworm infections are caused by fungi belonging to the genera Microsporum, trichophyton and Epidermophyton.
Ques. A person with sickle-cell anaemia is
(a) More prone to malaria (b) More prone to typhoid (c) Less prone to malaria (d) Less prone to typhoid
Sol. Sickle-cell anaemia is related to malaria not to typhoid and person suffering from sickle-cell anaemia are resistant to malarial parasite ar RBC of sickle-cell anaemic patients is distored in shape that not affected by Plasmodium $\mathrm{sp}$.
It is known that heterozygotes $\left(\mathrm{Hb}^{\mathrm{S}} / \mathrm{HB}^{\mathrm{A}}\right)$, having both types of haemoglobin show resistance to malarial infection because the body targets the $P$. falciparum infected cells for destruction.
In contrast, individuals homozygous for normal haemoglobin $\left(\mathrm{Hb}^{\mathrm{A}} / \mathrm{Hb}^{\mathrm{A}}\right)$ suffer high mortality rates in early childhood due to malarial infection.
Ques. Certain pathogens are tissue/organ specific.
Ans. Certain pathogens are tissue/organ specific as they are adapted to overcome the resistance mechanisms of those tissues and organs, e.g., the pathogens that enter the gut must know a way of surviving in the stomach at low $\mathrm{pH}$ and resistant to various digestive enzymes.
Ques. The immune system of a person is suppressed.
(a) Name the diseases the patient is suffering from. (b) What is the causative organisms? (c) Which cells of body are affected by the pathogen?
Ans. The immune system of a person is suppressed.
(a) The patient is suffering from AIDS. (b) AIDS is caused by Human Immuno deficiency Virus (HIV).
Ques. Where are B-cells and T-cells formed? How do they differ from each other?