Chapter 6 Part 4: Molecular Basis of Inheritance

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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p>This term has replaced the definition of a gene.</p>
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<p>Monocistronic transcription unit will have all the regulatory and coding sequences for a single polypeptide, whereas polycistronic may have coding sequences for more than one polypeptide.</p>
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<p>In eukaryotic cells almost all the messenger RNAs are monocistronic.</p>
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<p>In prokaryotes, lac operon coding sequence would be an example of polycistronic DNA region.</p>
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Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p>Actually, unwinding creates tension in the molecule as uncoiled parts start forming super coils due to the interaction of exposed nucleotides.</p>
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<p>Instead, helicase enzyme acts on the double strand at ori site (origin of replication) and a small stretch is unzipped.</p>
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<p>Immediately, it is held and stabilised by single strand binding proteins</p>
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<p><Success>Ans. to be continued</Success></p>
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Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<h4 id="primaryshort-answers-type-questionsprimary-27"><Primary>Short Answers Type Questions</Primary></h4>
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<p>Even if ${ }^{15} \mathrm{~N}$ was radioactive then its presence would have been detected, both inside the cell $\left({ }^{15} \mathrm{~N}\right).$ incorporated as introgenous base in DNA) as well as in the supernatant, because</p>
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<p>${ }^{15} \mathrm{~N}$ would also get incorporated in amino group of amino acids in proteins.</p>
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<p>Hence, the use of ${ }^{15} \mathrm{~N}$ would not give any conclusive results.</p>
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Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<h4 id="primaryshort-answers-type-questionsprimary-46"><Primary>Short Answers Type Questions</Primary></h4>
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<p><strong>Some important advantages</strong></p>
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<p>It provides the knowledge of the effects of variations of DNA among individuals can revolutionise the ways to diagnose, treat and prevent many diseases that affect humans.</p>
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<p>It also provides clues to the understanding of human biology.</p>
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<p>It helps to find out the human evolution.</p>
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<p>Identification through DNA forensics is also possible.</p>
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<p><Success>Ans. to be continued</Success></p>
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Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p><strong>Some important disadvantages</strong></p>
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<p>People might discover and untreatable genetic disease.</p>
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<p>People may abuse the knowledge obtained from the HGP.</p>
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<p>Problem can occur for the ownership of the genetic test result and the patenting of human genes and DNA.</p>
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<p>People believe that they are special and unique in their own ways and may wish to remain like that.</p>
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Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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