Chapter 6 Part 3: Molecular Basis of Inheritance

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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p><strong>Ans.</strong> Synthesis of DNA always takes place in $5^{\prime} \rightarrow 3^{\prime}$ direction.</p>
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<li>In a double stranded DNA both strands are anti parallel and complementary.</li>
<li>During DNA synthesis as both strands act as templates, only one strand, i.e., $3^{\prime} \rightarrow 5^{\prime}$ can synthesis complementary strand in $5^{\prime} \rightarrow 3^{\prime}$ direction.</li>
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<p><Success>Ans. to be continued</Success></p>
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Multiple choice questions (MCQs) $\rightarrow$ <span style="color:blue">Very short answer type questions</span> $\rightarrow$ Short answer type questions $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p><strong>Ans.</strong> DNA polymorphism refers to the variation in DNA arising through mutation at non-coding sequences.</p>
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<li>A special type of polymorphism, called VNTR (Variable Number of Tandem Repeats), is composed of repeated copies of a DNA sequence that lie adjacent to one another on the chromosome.</li>
<li>Since, polymorphism is the basis of genetic mapping of human genome, therefore, it forms the basis of DNA fingerprinting too.</li>
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<p><Success>Ans. to be continued</Success></p>
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Multiple choice questions (MCQs) $\rightarrow$ <span style="color:blue">Very short answer type questions</span> $\rightarrow$ Short answer type questions $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<p><strong>Ans.</strong> Due to point mutation in $\beta$-globin chain of haemoglobin molecule, glutamic acid (Glu) is replaced by valine ( $\mathrm{Val}$ ) at the sixth position.</p>
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<li>Under stress condition erythrocytes lose their circular shape and become sickle-shaped.</li>
<li>As a result, the cells cannot pass through narrow capillaries.</li>
<li>Blood capillaries are clogged and thus affect blood supply to different organs.</li>
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Multiple choice questions (MCQs) $\rightarrow$ <span style="color:blue">Very short answer type questions</span> $\rightarrow$ Short answer type questions $\rightarrow$ Long answer type questions
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<Success><font size="5"><b>Molecular Basis of Inheritance</b></font></Success>
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<h4 id="primaryshort-answers-type-questionsprimary-2"><Primary>Short Answers Type Questions</Primary></h4>
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<p><strong>Ans.</strong> In <strong>Griffith’s experiment</strong>, transformation can be defined as a change in the genetic constitution of an organism by picking out up DNA from the environment (from dead organisms).</p>
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<li>Transformation helps in identification of DNA as a genetic material.</li>
<li>When heat was used to kill the virulent bacteria, they died but not their genetic material (DNA).</li>
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<p><Success>Ans. to be continued</Success></p>
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<font size ="4">
<div style='text-align : center'>
Multiple choice questions (MCQs) $\rightarrow$ Very short answer type questions $\rightarrow$ <span style="color:blue">Short answer type questions</span> $\rightarrow$ Long answer type questions
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