Notes from NEET topper
Supporting Cells
Sertoli Cells: These cells line the seminiferous tubules and provide support, nutrition, and regulation to the developing sperm cells. They also form the blood-testis barrier, which protects the germ cells from harmful substances in the blood.
Leydig Cells: Located in the interstitial spaces between tubules, Leydig cells produce testosterone, the hormone essential for spermatogenesis and secondary male sexual characteristics.
Hormonal Regulation
FSH (Follicle-Stimulating Hormone): Stimulates spermatogenesis indirectly by acting on the Sertoli cells. LH (Luteinizing Hormone): Stimulates Leydig cells to produce testosterone. Testosterone: Essential for the final stages of spermatogenesis.
Clinical Relevance
Analysis of Seminiferous Tubules: Essential in evaluating male fertility. Issues in these tubules can lead to reduced sperm production or infertility. Effect of Hormones and Environmental Factors: Hormonal imbalances or exposure to certain environmental toxins can affect the functioning of seminiferous tubules.
