Notes from NEET topper

Phenotypic Ratio

In the context of principles of inheritance and variation, a “phenotypic ratio” refers to the ratio of different observable traits or phenotypes that are produced in the offspring of a genetic cross. The phenotypic ratio is determined by the combination of alleles inherited from the parents and their interactions, as governed by Mendel’s laws of inheritance.

1. Mendelian Inheritance: Phenotypic ratios are often associated with Mendelian inheritance patterns, which involve the segregation and assortment of alleles for specific traits.

2. Example: Consider a simple monohybrid cross involving two heterozygous individuals for a trait governed by a single gene. If the trait exhibits complete dominance, the phenotypic ratio in the offspring would typically be 3:1. This means that for every four offspring, three would exhibit one phenotype (dominant), and one would exhibit the other phenotype (recessive).

3. Dihybrid Cross: In dihybrid crosses, where two different traits are considered simultaneously, phenotypic ratios can become more complex. For example, in a dihybrid cross with complete dominance for both traits, the phenotypic ratio can be 9:3:3:1, representing various combinations of the dominant and recessive alleles for both traits.

4. Incomplete Dominance: In cases of incomplete dominance, where neither allele is completely dominant over the other, the phenotypic ratio can differ. For example, in a cross between red and white flowers resulting in pink flowers (incomplete dominance), the phenotypic ratio would be different from the typical Mendelian ratios.

5. Codominance: In codominance, both alleles for a trait are fully expressed in the heterozygous condition. In this case, the phenotypic ratio may involve more than two distinct phenotypes, depending on the specific trait.

6. Sex-Linked Traits: Phenotypic ratios can also be affected by the inheritance of traits linked to sex chromosomes (sex-linked traits), leading to different ratios for males and females.

7. Environmental Factors: It’s important to note that phenotypic ratios can be influenced by environmental factors in some cases. For example, temperature can affect the expression of certain traits in reptiles.

8. Predictive Tools: Geneticists use Punnett squares and probability calculations to predict phenotypic ratios based on the genotypes of the parents.



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