Notes from NEET topper

Chromosomal Mechanism Of Sex Determination

The chromosomal mechanism of sex determination is a genetic process by which an individual’s sex is determined based on the presence or combination of specific sex chromosomes. This mechanism is primarily observed in organisms with a chromosomal sex-determination system, and it contrasts with environmental sex determination, where factors such as temperature or social conditions influence an individual’s sex.

There are several chromosomal mechanisms of sex determination, and the two most common ones are the XX-XY system and the ZZ-ZW system, which are found in different species:

1. XX-XY System (Gonadal Sex Determination):

In this system, individuals have a pair of sex chromosomes, with one chromosome determining male sex (Y) and the other determining female sex (X).

In humans and many mammals, males have one X and one Y chromosome (XY), while females have two X chromosomes (XX).

The presence of the Y chromosome triggers the development of male reproductive structures, while the absence of the Y chromosome leads to the development of female reproductive structures.

The SRY (Sex-determining Region Y) gene on the Y chromosome plays a crucial role in male sex determination.

2. ZZ-ZW System (Gonadal Sex Determination):

This system is observed in some animals, including birds, reptiles, certain fish species, and some insects.

In this system, males typically have two of the same sex chromosomes (ZZ), while females have two different sex chromosomes (ZW).

The combination of ZZ or ZW determines the sex of the individual.

For example, in birds, males are ZZ, and females are ZW. The specific combination of chromosomes determines whether an individual is male or female.

3. Other Systems:

Some organisms have more complex chromosomal sex determination systems involving multiple sex chromosomes or additional genetic factors.

In some species, sex may be determined by the presence of specific genes on the sex chromosomes or by the dosage of certain genes.