Molecular Basis of Inheritance Question 44
44. The first phase of translation is
[2020]
(a) Recognition of DNA molecule
(b) Aminoacylation of tRNA
(c) Recognition of an anti-codon
(d) Binding of mRNA to ribosome
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Answer : b
Hints & Solution
(b) The first phase of translation involves activation of amino acid in the presence of ATP and linked to their cognate tRNA - a process commonly called as charging of tRNA or aminoacylation of tRNA. Mutations in transfer RNA genes reduce the ability of the tRNA to add amino acids to proteins, slowing protein production. Mutations that affect mitochondrial tRNAs impair the ability of mitochondria to provide energy for cells or to control blood sugar levels.