Molecular Basis of Inheritance Question 153
153. Expressed Sequence Tags (ESTs) refers to:
(a) Genes expressed as RNA
(b) Polypeptide expression
(c) DNA polymorphism
(d) Novel DNA sequences
Show Answer
Answer : a
Hints & Solution
(a) Expressed Sequence Tags (ESTs) are DNA sequences (genes) that are expressed as mRNA for protein synthesis. These are used in human Genome Project. Expressed Sequence Tags are small pieces of DNA sequence (usually 200 to 500 nucleotides long) that are generated by sequencing either one or both ends of an expressed gene. First, each gene (DNA) must be converted, or transcribed, into messenger RNA (mRNA)–RNA that serves as a template for protein synthesis.
