Digestion and Absorption Question 28
28. The enzyme enterokinase helps in conversion of
(a) trypsinogen into trypsin
(b) caseinogen into casein
(c) pepsinogen into pepsin
(d) protein into polypeptides
Show Answer
Answer : a
Hints & Solution
(a) The correct option is (a) because trypsinogen is activated by an enzyme, enterokinase, secreted by the intestinal mucosa into active trypsin. Trypsinogen is a zymogen from pancreas. Enterokinase is a sequence-specific protease that activates trypsinogen (276000) and has a major role in protein digestion. Deficiency of enterokinase is an autosomal recessive disorder characterized by severe protein malabsorption in early infancy, with failure to thrive, chronic diarrhea, and generalized edema.
