Biotechnology- Principles and Processes Question 51
51. Commonly used vectors for human genome sequencing are:
(a) T-DNA
(b) BAC and YAC
(c) Expression Vectors
(d) $kT /$ A Cloning Vectors
Show Answer
Answer : b
Hints & Solutions
(b) Human genome sequencing is a process that determines the complete DNA sequence of an organism’s genome at a single time. This requires sequencing all of an organism’s chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Commonly used vectors for human genome sequencing are $BAC$ (Bacterial artificial chromosome) and YAC (Yeast artificial chromosome). A P1-derived artificial chromosome (PAC) is a DNA construct that was derived from the DNA of P1 bacteriophage.
