Biotechnology- Principles and Processes Question 47
47. Choose the correct pair from the following [2020]
(a) Polymerases - Break the DNA into fragments
(b) Nucleases - Separate the two strands of DNA
(c) Exonucleases - Make cuts at specific positions within DNA
(d) Ligases - Join the two DNA molecules
Show Answer
Answer : a
Hints & Solutions
(a) Ligases join the two DNA molecules. DNA ligase is an enzyme which can connect two strands of DNA together by forming a bond between the phosphate group of one strand and the deoxyribose group on another. It is used in cells to join together the Okazaki fragments which are formed on the lagging strand during DNA replication. DNA Ligase I Deficiency Leads to ReplicationDependent DNA Damage and Impacts Cell Morphology without Blocking Cell Cycle Progression.
