Biotechnology and Its Applications Question 37

37. What is true for monoclonal antibodies? [2001]

(a) These antibodies obtained from one parent and for one antigen

(b) These antibodies obtained from parent and for two antigen

(c) These antibodies obtained from one parent and for many antigen

(d) These antibodies obtained from many parents and for many antigens

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Answer : a

Hints & Solutions

(a) Monoclonal antibodies are identical molecules specific for one type of antigen. These are obtained by injecting the target antigen into a rat or mouse. Sometimes later, the spleen cells producing antibodies are isolated and fused with myeloma cells to produce monoclonal antibodies.