Biotechnology and Its Applications Question 28

28. Which of the following statements is not correct?

[2020]

(a) The proinsulin has an extra peptide called C-peptide.

(b) The functional insulin has A and B chains linked together by hydrogen bonds.

(c) Genetically engineered insulin is produced in E.Coli.

(d) In man insulin is synthesised as a proinsulin

Show Answer

Answer : b

Hints & Solutions

(b) The correct option is

(b) because functional insulin has A and B chains linked together by disulphide bridges. Insulin molecules have a tendency to form dimers in solution due to hydrogen-bonding between the C-termini of B chains.